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Chittibabu, C. V.
- In vitro Antibacterial Activity and Phytochemical Composition of Kedrostis foetidissima (Jacq.) Cogn.
Authors
1 Dept of Botany, Bharathi Women's College (Autonomous), Chennai- 600108, IN
2 Prist University, Thanjavur, TN-613001, IN
3 Research Dept of Botany, Govt Arts College for Men(Autonomous), Nandanam, Chennai-600035, IN
Source
Indian Journal of Drugs and Diseases, Vol 3, No 1 (2014), Pagination: 305-310Abstract
Objectives: In this study the phytochemical composition of the methanolic leaf extracts of Kedrostis foetidissima (Jacq.) Cogn., and its antibacterial activity against Klebsiella pneumoniae, Shigella sonnei, Salmonella typhi and Vibrio cholerae were evaluated.
Methods: The antibacterial activity of the methanolic leaf extract was done by Agar Well diffusion assay. Broth dilution assay was used to determine the Minimum Inhibitory Concentration (MIC). Quantitative and qualitative phytochemical analysis for the methanolic leaf extract was carried out using standard protocols. Chromatographic and GC-MS analysis of the crude leaf extracts were also carried out.
Results: Among the four test bacteria used, the methanolic leaf extract showed greater antibacterial activity on Klebsiella pneumoniae with a maximum growth inhibition of 33 mm diameter at its MIC value of 100 μg/ml. The phytochemical analysis of methanolic leaf extract confirmed the high level presence of alkaloids and flavonoids (19.85%; 21.68% respectively of the dry weight of the extract) followed by phenols (3.84%) and reducing sugars. TLC showed six different bioactive components as detected by UV and two by Iodine chamber; while GC-MS analysis revealed the presence of around 59 compounds.
Conclusion: The usage of the leaves of this plant as an effective medicine against cough, cold, asthma and other respiratory ailments in infants and adults could be due to the antibacterial activity of the leaf extract and higher quantity of alkaloids and flavonoids found in it.
Keywords
Kedrostis Foetidissima, Antibacterial Activity, Phytochemical Analysis, TLC, GC-MSFull Text
- Ethnobotanical Investigation on the Malayali Tribes in Javadhu Hills, Eastern Ghats, South India
Authors
1 PG and Research Department of Botany, Government Arts College for Men (Autonomous), Nandanam, Chennai 600035, Tamil Nadu, IN
Source
Indian Journal of Medicine and Healthcare, Vol 3, No 1 (2014), Pagination: 322-332Abstract
An ethnobotanical investigation was conducted in Javadhu hills of Eastern Ghats, Thiruvannamalai District, Tamil Nadu, South India, by collecting information from the Malayali tribes through interviews, structured questionnaires and group discussion during September 2012 to August 2013. A total of 11 Malayali tribes cooperated with the researchers to share their traditional knowledge and helped in the collection of 110 medicinal plants. The collected plants are listed with their botanical, local and family names along with the details of part(s) used, traditional use and ethnomedicinal preparation. It was found that the 110 plant species belonging to 100 genera and 51 plant families were traditionally used to cure 17 human ailments. The maximum number of plants species (26) was used for Gastro-Intestinal Diseases (GID), 16 plant species each for Dermatological Infections/Diseases (DID) and Skeleto-Muscular System Disorders (SMSD), and 11 for Respiratory System Diseases (RSD). The analysis of different plant parts used to cure diseases revealed that leaves were the most widely used plant part, which accounted for 59 species out of 110 reported medicinal plants in this study, followed by ischolar_main (15 species) and fruit (12 species). The majority of the ethnomedicinal preparation type was in the form of paste from 54 plants (49%). The results showed that the Malayali tribes depended heavily on the medicinal plants of the hills inhabited by them, stressing the need for revival of interest in ethnomedicine. Documentation of ethnobotanical knowledge is the need of the hour as it may carry solution for unsolved areas like 'cancer' and 'ageing', besides adding wealth of knowledge to 'Green medicine'.Keywords
Ethnobotany, Malaiyali Tribes, Medicinal Plants, Javadhu Hills, EthnomedicineFull Text
- Gastrointestinal Disease Management through Ethnobotanical Approach by Malayali Tribes of Javadhu Hills, South India
Authors
1 Department of Plant Biology and Plant Biotechnology, Presidency College (Autonomous), Chennai-600 005, Tamil Nadu, IN
Source
Indian Journal of Medicine and Healthcare, Vol 4, No 3 (2015), Pagination: 1-6Abstract
Objective: The present study was aimed at recording the usage of herbals for gastrointestinal diseases by Malayali tribes in Javadhu Hills of Tamil Nadu.
Methods: A field survey in four villages of Javadhu Hills was systematically conducted. Eleven Malayali tribal healers of the study area were interviewed through structured questionnaire for their knowledge on the utilization of herbals for gastrointestinal diseases.
Results: A total of 31 species of ethnomedicinal plants (herbals) belonging to 22 families, comprising 27 Dicotyledons and 4 Monocotyledons were found to be used by Malayali tribes in Javadhu Hills. The Malayali tribes possess an appreciable knowledge on the usage of herbals for gastrointestinal diseases when compared to their counterpart in Gingee Hills, Villupuram district.
Conclusion: Investigation of this kind will help in augmenting herbal research in various dimensions of human healthcare, besides documenting the traditional knowledge from oblivion.
Keywords
Ethnobotany, Malayali Tribes, Javadhu Hills, Herbal Plants, Gastrointestinal Diseases.Full Text
- A Comparative in Vitro Antibacterial Activity Study on Indian Medicinal Plants
Authors
1 Department of Plant Biology, Presidency College, Chennai, Tamil Nadu, IN
Source
Indian Journal of Innovations and Developments, Vol 4, No 8 (2015), Pagination: 1-5Abstract
Objective: The aim of the study was to find the anti bacterial activity of five Indian medicinal plants namely, Abutilon indicum, Azadirachta indica, Leucas aspera, Ocimum sanctum and Vitex negundo against human pathogens Bacillus subtilis, Escherichia coli and Klebsiella pneumonia.
Methods: The methanol, acetone, and ethanol leaf extracts were studied for their activity against human pathogens using well diffusion method.
Results: The results of this study showed that acetone extracts of all the five medicinal plants used against Bacillus subtilis, Escherichia coli and Klebsiella pneumonia revealed better antibacterial activity compared to those of methanol and ethanol extracts. Further, the acetone leaf extract of Vitex negundo exhibited maximum inhibition zone against K. pneumonia and B. subtilis than the other acetone leaf extracts of medicinal plants experimented in the study. The maximum zone of inhibition (20 mm and 19 mm respectively) of acetone leaf extract of Vitex negundo was against Klebsiella pneumonia and Bacillus subtilis. The acetone leaf extract of Leucas aspera showed minimum inhibitory antibacterial activity (7 mm inhibitory zone) against E. coli. Whereas, the leaf extracts of Abutilon indicum, Azadirachta indica and Ocimum sanctum showed moderate antibacterial activity (between 8 and 13 mm).
Conclusion: The study records the in vitro validation for the traditional use of these herbals in the treatment of bacterial infections. However, further clinical studies are required for assessing the real potentials and safety aspects of these herbal drugs.
Keywords
Antibacterial, Indian Medicinal Plants, Human Pathogens, Acetone Leaf Extracts, Well Diffusion Method.Full Text